PNU-282987 S enantiomer hydrochloride

SKU: orb1704799

Description

(S)-PNU-282987 is the enantiomerically pure form of a potent and selective α7 nicotinic acetylcholine receptor agonist (Ki = 26 nM). It exhibits negligible activity at other major nAChR subtypes and neurotransmitter receptors, except for moderate 5-HT3 receptor affinity. This selectivity makes it a valuable research tool for investigating α7 nAChR function in neuropsychiatric and neurodegenerative disease models, both in vitro and in vivo.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 128311-08-0
• MW: 301.21
• Formula: C₁₄H₁₈Cl₂N₂O
• SMILES: Cl.Clc1ccc(cc1)C(=O)N[C@@H]1CN2CCC1CC2 |THB:10:11:15.14:18.17|
• Target: Others,5-HT Receptor,AChR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

18645636