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PNU-282987 S enantiomer hydrochloride

PNU-282987 S enantiomer hydrochloride

Catalog Number: orb1704799

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Catalog Numberorb1704799
CategorySmall Molecules
DescriptionPNU-282987 S enantiomer hydrochloride
Purity98.00%
MW301.21
Biological Activity(S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, glutamate, muscarinic,and GABA receptors, except 5-HT3 with Ki of 930 nM.
CAS Number128311-08-0
FormulaC14H18Cl2N2O
SMILESCl.Clc1ccc(cc1)C(=O)N[C@@H]1CN2CCC1CC2 |THB:10:11:15.14:18.17|
Storage-20°C
NoteFor research use only