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Catalog Number | orb1704799 |
---|---|
Category | Small Molecules |
Description | PNU-282987 S enantiomer hydrochloride |
Purity | 98.00% |
MW | 301.21 |
Biological Activity | (S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, glutamate, muscarinic,and GABA receptors, except 5-HT3 with Ki of 930 nM. |
CAS Number | 128311-08-0 |
Formula | C14H18Cl2N2O |
SMILES | Cl.Clc1ccc(cc1)C(=O)N[C@@H]1CN2CCC1CC2 |THB:10:11:15.14:18.17| |
Storage | -20°C |
Note | For research use only |