PNR-3-82

SKU: orb3173262

Description

PNR-3-82 is a selective inhibitor of Endonuclease G (EndoG) with an IC50 of 0.61 μM, showing greater efficacy than its inhibition of DNase I. It does not inhibit five enzymes related to cell death: DNase II, RNase A, protease, lactate dehydrogenase, and superoxide dismutase 1. With cytoprotective properties, PNR-3-82 prevents cell death induced by cisplatin and docetaxel and can be utilized in cell damage research.

Key Properties

• CAS Number: 1424353-64-9
• MW: 455.49
• Formula: C₂₅H₁₇N₃O₄S
• SMILES: O=C1NC(=S)NC(=O)C1=CC2=CN(C(=O)C=3C=CC=4C=CC=CC4C3)C=5C=CC(OC)=CC25
• Target: Endonuclease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Endonuclease