PM050489

SKU: orb1981916

Description

PM050489 is a potent microtubule/tubulin polymerization inhibitor isolated from the sponge Lithoplocamia lithistoides, exhibiting antitumor activity with a mitotic inhibition IC₅₀ of 26.4 nM. It serves as a valuable chemical tool for cancer research, particularly in studying cell division mechanisms and evaluating antitumor efficacy in both cellular and animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 960210-97-3
• MW: 606.15
• Formula: C₃₁H₄₄ClN₃O₇
• SMILES: [C@@H](/C=C(/C=C\C=C/C(N[C@H](C(N/C=C\C[C@H](C/C=C(\C)/Cl)OC(N)=O)=O)[C@@](C)(C)C)=O)\C)(C)[C@]1(OC(=O)C(OC)=CC1)[H]
• Target: Microtubule Associated,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57788248