PLX647 dihydrochloride

SKU: orb1691497

Description

PLX647 dihydrochloride is a potent, orally active dual inhibitor of FMS (IC50=28 nM) and KIT (IC50=16 nM) kinases with high selectivity across the kinome. It has been utilized in preclinical research to investigate the roles of these kinases in oncology, inflammation, and neurological disease models, both in vitro and in vivo.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1779796-38-1
• MW: 455.31
• Formula: C₂₁H₁₉Cl₂F₃N₄
• SMILES: Cl.Cl.FC(F)(F)c1ccc(CNc2ccc(Cc3c[nH]c4ncccc34)cn2)cc1
• Target: c-Kit,c-Fms,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

78243730