PLP (178-191)

SKU: orb1943326

Description

PLP (178-191) is a key encephalitogenic epitope in SJL mice, inducing earlier disease onset than the PLP (139-151) epitope while yielding comparable disease incidence and pathology. This peptide is a critical tool for studying experimental autoimmune encephalomyelitis (EAE) in vivo, facilitating research into multiple sclerosis mechanisms and immunomodulatory therapies.

Key Properties

• CAS Number: 172228-98-7
• MW: 1583.76
• Formula: C₇₀H₁₀₆N₁₈O₂₂S
• SMILES: C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N1[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CO)=O)CCC1)CC2=CC=CC=C2)=O)C)=O)[C@H](CC)C)=O)CO)=O)CCC(N)=O)=O)CS)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)NC([C@@H](NC([C@H](CC(N)=O)N)=O)[C@@H](C)O)=O)C=3C=4C(NC3)=CC=CC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16131190