PLK4-IN-4

SKU: orb2283533

Description

PLK4-IN-4 (compound 22) is a potent and selective PLK4 inhibitor with an IC50 of 7.9 nM. This small molecule is a valuable chemical probe for studying polo-like kinase 4 function in centrosome duplication, applicable in both in vitro biochemical assays and in vivo cancer research models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2923999-01-1
• MW: 439.46
• Formula: C₂₁H₂₃F₂N₉
• SMILES: N(C1=C2C(N(N=C2)C3CCNCC3)=NC(NCC4=C(F)C=C(F)C=C4)=N1)C=5C=C(C)NN5
• Target: Others,PLK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168279678