PLK1/BRD4-IN-3

SKU: orb2564703

Description

Compound 21 (PLK1/BRD4-IN-3) is a potent dual inhibitor of BRD4 and PLK1 kinases, with IC50 values of 0.059 µM and 0.127 µM, respectively. This small molecule is a valuable chemical probe for cancer research, utilized in both in vitro and in vivo studies to investigate oncogenic signaling pathways.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2251709-91-6
• MW: 561.72
• Formula: C₃₁H₄₃N₇O₃
• SMILES: C[C@@H]1N(C=2C(=CN=C(NC3=C(OC4CCCC4)C=C(C(NC5CCN(C)CC5)=O)C=C3)N2)N(C)C1=O)C6CCCC6
• Target: PLK,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145976646