PLK1/BRD4-IN-2

SKU: orb2565464

Description

PLK1/BRD4-IN-2 (compound 15) is a dual inhibitor derived from BI-2536, potently targeting both PLK1 (IC50 = 40 nM) and the BRD4 bromodomain (IC50 = 28 nM). This small molecule is a valuable chemical probe for cancer research, enabling the study of concurrent PLK1 and BRD4 inhibition in cellular and biochemical assays.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2251709-89-2
• MW: 492.61
• Formula: C₂₇H₃₆N₆O₃
• SMILES: C[C@H]1N(C=2C(N(C)C1=O)=CN=C(NC3=C(OC)C=C(C(=O)N4CCCCCC4)C=C3)N2)C5CCCC5
• Target: Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171391380