PLK1-IN-9

SKU: orb2564718

Description

PLK1-IN-9 (Compound M2) is a potent PLK1 inhibitor with IC50 values in the sub-micromolar range against key phosphopeptide substrates. It demonstrates robust anti-proliferative and pro-apoptotic activity in various cancer cell lines (e.g., HeLa, HepG2) and has shown efficacy in suppressing tumor growth in a HepG2 xenograft model, supporting its use in oncology research.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 893772-67-3
• MW: 296.20
• Formula: C₁₂H₇F₃N₄O₂
• SMILES: O=C1N=C2C(=NC=3C=C(C=CC3N2C)C(F)(F)F)C(=O)N1
• Target: PLK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5311789