PLD-IN-1

SKU: orb2695416

Description

PLD-IN-1 (Compound 3r) is an orally active phospholipase D inhibitor (IC50=1.97 μM) that modulates tumor immunogenicity by altering CD24, CD47, PD-L1, and calreticulin expression. It demonstrates anti-proliferative and pro-apoptotic effects in lung cancer cell lines and shifts macrophage polarization toward the M1 phenotype, showing efficacy in vivo.

Research Area

Cell Biology, Metabolism Research

Key Properties

• MW: 400.32
• Formula: C₁₉H₁₄F₆N₂O
• Target: Apoptosis,Phospholipase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Apoptosis,Phospholipase