PKMYT1-IN-8

SKU: orb2945962

Description

PKMYT1-IN-8 (Compound 137) is a potent, nanomolar-range PKMYT1 inhibitor (IC50 = 9 nM) with additional micromolar activity against several EPH receptors and KIT. It demonstrates anti-proliferative activity in OVCAR3 cancer cells (GI50 = 2.02 µM), supporting its use in cell-based assays for oncology research, particularly in studying cell cycle regulation and kinase signaling pathways.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3065631-84-4
• MW: 379.336
• Formula: C₁₇H₁₆F₃N₅O₂
• SMILES: CC1=C(C(=C(C=C1)O)C)N2C(=C(C3=C(N=C(N=C32)C)C(F)(F)F)C(=O)N)N
• Target: Ephrin Receptor,Wee1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172625958