PKMYT1-IN-1

SKU: orb2565466

Description

PKMYT1-IN-1 (Compound 1) is a potent and selective PKMYT1 kinase inhibitor with an enzymatic IC₅₀ of 8.8 nM. It demonstrates anti-proliferative activity in HCC1569 tumor cells (IC₅₀ = 42 nM), supporting its use as a chemical probe for studying cell cycle regulation and DNA damage response pathways in cancer research.

Research Area

Cell Biology

Key Properties

• CAS Number: 3033609-83-2
• MW: 371.39
• Formula: C₂₁H₁₇N₅O₂
• SMILES: NC1=C2C3=C(N1C4=C(C)C(O)=CC=C4C)N=CN=C3C=5C(NC2=O)=CC=CC5
• Target: Others,Wee1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171391442