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PKM2/PDK1-IN-1

SKU: orb1982596

Description

PKM2/PDK1-IN-1 is a shikonin-derived dual PKM2/PDK1 inhibitor. It suppresses proliferation and triggers apoptosis in non-small cell lung cancer (NSCLC) cells via ROS generation and activation of mitochondrial and death receptor pathways, making it a useful research tool for oncology studies.

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

MW697.92
FormulaC36H43NO7S3
TargetOthers,Akt,EGFR,Apoptosis,PKM,PDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information