PKM2 agonist-1

SKU: orb3174918

Description

PKM2 agonist-1 (Compound D16) is a potent allosteric activator of PKM2, with an AC50 value of 77 nM. It inhibits angiotensin II-induced smooth muscle cell phenotypic transformation, effectively preventing aortic dissection and reducing mortality.

Research Area

Metabolism Research

Key Properties

• CAS Number: 3075162-42-1
• MW: 509.6
• Formula: C₂₄H₂₃N₅O₄S₂
• SMILES: O=S(=O)(NC=1C=CC(=CC1)C2=NC=CN2C3CN(C3)S(=O)(=O)C4CC4)C5=CC=CC6=CC=CN=C65
• Target: PKM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PKM