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PKM2 activator 6

SKU: orb1943319

Description

Compound Z10 is a dual-action small molecule functioning as a PKM2 activator (K_D = 121 µM) and a PDK1 inhibitor (K_D = 19.6 µM). It suppresses proliferation, migration, and glycolysis while inducing apoptosis in colorectal cancer cell lines such as DLD-1, HCT-8, and HT-29, making it a useful tool for studying cancer metabolism in vitro.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

TargetPDK,Others,PKM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information