PKI-179 hydrochloride

SKU: orb1694054

Description

PKI-179 is a potent and selective oral dual inhibitor of PI3K and mTOR, effective against common PI3Kα mutants. It demonstrates robust anti-proliferative activity in breast and prostate cancer cell lines and inhibits tumor growth in a mouse xenograft model, making it a valuable tool for oncology research targeting the PI3K/Akt/mTOR pathway.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1463510-35-1
MW	525
Formula	C₂₅H₂₉ClN₈O₃
SMILES	Cl.O=C(Nc1ccncc1)Nc1ccc(cc1)-c1nc(nc(n1)N1CCOCC1)N1C2CCC1COC2
Target	Others,mTOR,PI3K

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

137699924 ↗

Key Properties

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No computed properties available.

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