PKI-166 hydrochloride

SKU: orb1693562

Description

This orally bioavailable, potent, and selective EGFR kinase inhibitor (IC50 = 0.7 nM) demonstrates significant anti-metastatic and anti-angiogenic activity in pancreatic cancer mouse models. It is a valuable research tool for studying EGFR-driven oncology, with applications in both in vitro biochemical assays and in vivo preclinical research.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2230253-82-2
• MW: 366.85
• Formula: C₂₀H₁₉ClN₄O
• SMILES: Cl.C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1
• Target: EGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91691117