PKI-166 hydrochloride

SKU: orb1693562

Description

This orally bioavailable, potent, and selective EGFR kinase inhibitor (IC50 = 0.7 nM) demonstrates significant anti-metastatic and anti-angiogenic activity in pancreatic cancer mouse models. It is a valuable research tool for studying EGFR-driven oncology, with applications in both in vitro biochemical assays and in vivo preclinical research.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2230253-82-2
MW	366.85
Formula	C₂₀H₁₉ClN₄O
SMILES	Cl.C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1
Target	EGFR,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

91691117 ↗

Key Properties

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No computed properties available.

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