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PKI 14-22 amide, myristoylated Acetate

SKU: orb1306131

Description

This myristoylated PKI 14-22 amide acetate is a potent and cell-permeable inhibitor of cAMP-dependent protein kinase (PKA). It effectively blocks PKA activity in vitro and inhibits hyperalgesia in vivo, as demonstrated by its ability to counteract pain sensitization induced by spinal 8-bromo-cAMP.

Research Area

Signal Transduction

Images & Validation

Key Properties

TargetPKA
Molecular Weight1269.54
Purity96.34%
FormulaC55H104N20O14
SMILESCC[C@H](C)[C@@H](C(N)=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC(CNC(CCCCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O

Storage & Handling

Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PKI 14 22 amide, myristoylated Acetate, PKI 1422 amide, myristoylated Acetate, PKI 14-22 amide, myristoylated Acetate, PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base), PKA
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Key Properties

No computed properties available.

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Protocol Information

PKI 14-22 amide, myristoylated Acetate (orb1306131)

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1 mg
$ 220.00
5 mg
$ 450.00
10 mg
$ 640.00
1 ml x 10 mM (in DMSO)
$ 820.00
25 mg
$ 930.00
50 mg
$ 1,230.00
100 mg
$ 1,650.00
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