PKCTheta-IN-1

SKU: orb2565469

Description

PKCTheta-IN-1 (Compound 19) is a highly potent macrocyclic inhibitor of PKCθ, exhibiting an IC₅₀ of 0.1 nM. This inhibitor is a valuable research tool for studying T-cell signaling and immune regulation in both cellular assays and animal models of autoimmune and inflammatory diseases.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2948289-20-9
• MW: 380.4
• Formula: C₁₉H₂₀N₆O₃
• SMILES: O=C1N2C=3C(N1)=NC=CC3O[C@H](C)CCN4C5=NC2=CC=C5C(=O)NC4(C)C
• Target: PKC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168951642