PKCiota-IN-1

SKU: orb1744569

Description

PKCiota-IN-1 is a highly potent and selective small molecule inhibitor of protein kinase C iota (PKCι), with an IC50 of 2.7 nM. It also inhibits PKC-α and PKC-ε at higher concentrations. This compound is a valuable chemical probe for studying PKCι signaling in cancer cell proliferation and transformation in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2230052-97-6
• MW: 427.47
• Formula: C₂₅H₂₂FN₅O
• SMILES: O(C)C1=C(C2=C3N(N=C2)C=CC(=C3)C4=C5C(=NC=C4)NC=C5)C=C6C(=C1)CC(CF)NC6
• Target: PKC,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145967445