PKC-theta inhibitor 1

SKU: orb1708842

Description

PKC-theta inhibitor 1 is a potent and selective small molecule antagonist of protein kinase C theta (PKCθ), exhibiting a Ki of 6 nM. This compound is a valuable research tool for investigating T-cell activation and signaling pathways in immunological and inflammatory disease models, both in cellular assays and in vivo studies.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1160501-81-4
• MW: 348.32
• Formula: C₁₇H₁₅F₃N₄O
• SMILES: C(F)(F)(F)C=1C2=C(C=CN=C2NN1)C3=CC(=CC=C3)C4(CN)COC4
• Target: PKC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57969746