PKA Inhibitor Fragment (6-22) amide TFA

SKU: orb1981568

Description

PKA Inhibitor Fragment (6-22) amide TFA is a potent and selective cyclic AMP-dependent protein kinase A (PKA) inhibitor with a Ki of 2.8 nM. It is widely used in biochemical assays to study PKA signaling and has been shown in vivo to reverse the analgesic effects of low-dose morphine in mouse models.

Research Area

Immunology & Inflammation; Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: PKA
• MW: 1982.08
• Purity: 99.61% (May vary between batches)
• Formula: C₈₂H₁₃₁F₃N₂₈O₂₆
• SMILES: CC[C@H](C)[C@@H](C(N)=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](C)NC([C@@H](NC([C@@H](N)[C@H](O)C)=O)CC1=CC=C(C=C1)O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PKA, PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base), PKI-(6-22)-amide TFA

Compound Identifiers

PubChem CID

145707888