Pixatimod

SKU: orb2815258

Description

Pixatimod (PG-545) is a synthetic heparan sulfate mimetic and TLR9 agonist with demonstrated immunostimulatory, antitumor, and antiviral activity. It inhibits SARS-CoV-2 entry and suppresses tumor progression in numerous preclinical in vivo models, showing combinatory potential with various chemotherapies and immunotherapies.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 1144617-49-1
• MW: 2078.05
• Formula: C₅₁H₈₈O₆₀S₁₃
• SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC[C@]1(C[C@@H](O[C@H]5[C@H](OS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@H](O[C@@H]6[C@H](OS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@H](O[C@@H]7[C@H](OS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@H](O[C@@H]8[C@H](OS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@@H](COS(=O)(=O)O)O8)[C@@H](COS(=O)(=O)O)O7)[C@@H](COS(=O)(=O)O)O6)[C@@H](COS(=O)(=O)O)O5)CC2)[H])[H])[H]
• Target: SARS-CoV,TLR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57412325