Pixantrone dimaleate

SKU: orb1305549

Description

Pixantrone dimaleate, also known as BBR 2778, is a synthetic aza-anthracenedione investigational agent for research use. It functions as a DNA intercalator and topoisomerase II inhibitor, with demonstrated antitumor activity in both in vitro cell line studies and in vivo animal models of lymphoma and breast cancer.

Research Area

Molecular Biology

Key Properties

• CAS Number: 144675-97-8
• MW: 557.21
• Purity: 99.28% (May vary between batches)
• Formula: C₂₅H₂₇N₅O₁₀
• SMILES: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.NCCNc1ccc(NCCN)c2C(=O)c3cnccc3C(=O)c12
• Target: Topoisomerase
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.79 mM);DMSO:91 mg/mL (163.31 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MDCK cell, intercalator, K562 cell, BBR 2778, BBR 2778 dimaleate, BBR2778, BBR-2778, BBR2778 Dimaleate, BBR-2778 Dimaleate, Topoisomerase, Pixantrone Maleate, Pixantrone, Pixantrone dimaleate

Compound Identifiers

PubChem CID

9937618