Pitofenone hydrochloride

SKU: orb1302836

Description

Pitofenone hydrochloride is a spasmolytic agent that acts as an acetylcholinesterase (AChE) inhibitor, demonstrating Kis of 36 μM and 45 μM against bovine erythrocyte and electric eel enzymes, respectively. This compound is a useful research tool for studying cholinergic signaling and smooth muscle spasmolysis in biochemical and pharmacological assays.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1248-42-6
• MW: 403.9
• Purity: 99.97% (May vary between batches)
• Formula: C₂₂H₂₆ClNO₄
• SMILES: Cl.COC(=O)c1ccccc1C(=O)c1ccc(OCCN2CCCCC2)cc1
• Target: Cholinesterase (ChE)
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.48 mM);DMSO:45 mg/mL (111.41 mM)

Bioactivity

• Target IC50:
  AChE (electric eel):Ki:45 μM|AChE (bovine erythrocytes):Ki:36 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Baralgin Ketone Hydrochloride, AChE, Cholinesterase (ChE), Pitophenone Hydrochloride, Pitophenone hydrochloride, Pitofenone, Pitofenone hydrochloride, Pitofenone Hydrochloride

Compound Identifiers

PubChem CID

121097