Pirozadil

SKU: orb1302070

Description

Pirozadil is a small molecule compound exhibiting lipid-lowering properties. It is utilized in biochemical research to study hypolipidemic mechanisms and has been investigated in both in vitro assays and animal models for its effects on lipid metabolism.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 54110-25-7
• MW: 527.52
• Purity: 98.77% (May vary between batches)
• Formula: C₂₇H₂₉NO₁₀
• SMILES: COc1cc(cc(OC)c1OC)C(=O)OCc1cccc(COC(=O)c2cc(OC)c(OC)c(OC)c2)n1
• Target: Others
• Solubility: DMSO:13.75 mg/mL (26.07 mM);H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.79 mM)

Bioactivity

• In Vivo:
  After a 3 month treatment with Pirozadil period, a significant reduction in plasma cholesterol from 299.8 +/- 31.2 mg/dl to 256.8 mg/dl and Low-Density Lipoprotein (LDL) cholesterol from 211.7 mg/dl to 168.8 mg/dl was observed. High Density Lipoprotein (HDL) cholesterol was unchanged. The drug was well tolerated with no side effects noted.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Pirozadil

Compound Identifiers

PubChem CID

68711