Pirfenidone

• Catalog Number: orb1305557
• Category: Small Molecules
• Description: Pirfenidone
• Purity: 99.79%
• MW: 185.22
• Biological Activity: Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis.
• CAS Number: [53179-13-8]
• Formula: C₁₂H₁₁NO
• SMILES: O=C1N(C=C(C)C=C1)C2=CC=CC=C2
• Storage: -20°C
• Note: For research use only