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    Pirarubicin HCl

    Pirarubicin HCl

    Catalog Number: orb1737781

    DispatchUsually dispatched within 6-8 weeks
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    Catalog Numberorb1737781
    CategorySmall Molecules
    DescriptionPirarubicin HCl
    CAS Number95343-20-7
    Purity0.98
    MW664.1
    SMILESCl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O[C@@H]6CCCCO6)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
    FormulaC32H38ClNO12
    Biological ActivityPirarubicin HCl is the hydrochloride salt form of pirarubicin, an analogue of the anthracycline antineoplastic antibiotic doxorubicin with antineoplastic activity. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
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