Pipobroman

SKU: orb1302748

Description

Pipobroman (Vercyte) is an alkylating agent with established clinical efficacy in polycythemia vera and essential thrombocythemia, achieving high response rates with a favorable long-term risk profile for thrombosis and leukemic transformation. Its research applications include in vitro studies on hematopoietic cell lines and in vivo models of myeloproliferative neoplasms to investigate its antiproliferative mechanisms.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 54-91-1
• MW: 356.05
• Purity: 93.01% (May vary between batches)
• Formula: C₁₀H₁₆Br₂N₂O₂
• SMILES: BrCCC(=O)N1CCN(CC1)C(=O)CCBr
• Target: DNA Alkylator/Crosslinker,DNA/RNA Synthesis
• Solubility: H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.62 mM);DMSO:60 mg/mL (168.52 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Crosslinker, cutaneous squamous cell carcinoma, DNAAlkylator, DNA Alkylator, DNA Alkylator/Crosslinker, AML, A8103, A-8103, A 8103, Amedel, Inhibitor, inhibit, myeloproliferative neoplasm, MDS, Vercyte, Polycythemia vera, thrombosis, Pipobroman

Compound Identifiers

PubChem CID

4842