Piperazine adipate

SKU: orb1220532

Description

Piperazine adipate is a potent broad spectrum anthelmintic.(In Vitro):Piperazine adipate (10 mM) causes mortality of A. galli and H. gallinae after a maximum of 30 min exposure, inhibits malate oxidation by 78%, and inhibits aldolase activity in both parasites. Piperazine adipate (10 mM) also inhibits cholinesterase activity by 96% in Ascaridia galli (A. galli) and 93% in Heterakis gallinae (H. gallinae). Piperazine adipate inhibits oxaloacetate reduction by 26% and 55% in A. galli and H. gallinae, resepctively.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	142-88-1
MW	232.28
Purity	>98% (HPLC)
Formula	C₁₀H₂₀N₂O₄
SMILES	C1CNCCN1.OC(=O)CCCCC(O)=O
Target	Parasite
Solubility	H2O:14.29 mg/mL (61.52 mM; Need ultrasonic)

Bioactivity

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In Vitro

Piperazine adipate (10 mM) causes mortality of A. galli and H. gallinae after a maximum of 30 min exposure, inhibits malate oxidation by 78%, and inhibits aldolase activity in both parasites. Piperazine adipate (10 mM) also inhibits cholinesterase activity by 96% in Ascaridia galli (A. galli) and 93% in Heterakis gallinae (H. gallinae). Piperazine adipate inhibits oxaloacetate reduction by 26% and 55% in A. galli and H. gallinae, resepctively.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Parasite

Protocol Information

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Purity:	99.90% (May vary between batches)
CAS Number:	142-88-1
MW:	232.28
Formula:	C₁₀H₂₀N₂O₄