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PIN1 inhibitor API-1

SKU: orb1307873

Description

PIN1 inhibitor API-1

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number680622-70-2
MW366.3
Purity98.48% (May vary between batches)
FormulaC15H13F3N6O2
SMILESNc1nc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)c2[nH]cnc2n1
TargetMicroRNA
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.65 mM);DMSO:250 mg/mL (682.5 mM)

Bioactivity

Target IC50
Pin1:72.3 nM
In Vivo
PIN1 inhibitor API-1 inhibits tumor growth by up-regulating mature miRNA biogenesis in mice .
In Vitro
PIN1 inhibitor API-1 significantly suppresses SK-Hep-1, SNU-423, and Hep3B cell proliferation (IC50=0.683-4.16 μM).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MicroRNA, miRNA, Inhibitor, inhibit, PIN1 inhibitor API 1, PIN1 inhibitor API1, PIN-1 inhibitor API-1, PIN1 inhibitor API-1, Pin1

Similar Products

  • PIN1 inhibitor API-1 [orb1217737]

    >98% (HPLC)

    680622-70-2

    366.3

    C15H13F3N6O2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 170.00
1 ml x 10 mM (in DMSO)
$ 190.00
10 mg
$ 290.00
25 mg
$ 410.00
50 mg
$ 580.00
100 mg
$ 720.00
200 mg
$ 990.00
500 mg
$ 1,420.00
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