PIM-1/HDAC-IN-1

SKU: orb1688525

Description

PIM-1/HDAC-IN-1 is a dual-targeting inhibitor with potent activity against PIM-1 (IC50 343.87 nM) and selective inhibition of HDAC1/6 (IC50 ~63 nM). It induces apoptosis and G2/M phase arrest in MCF-7 breast cancer cells, making it a valuable chemical probe for oncology research targeting epigenetic and kinase pathways.

Research Area

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• MW: 373.4
• Formula: C₂₂H₁₉N₃O₃
• Target: HDAC,Pim,Apoptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HDAC,Pim,Apoptosis,Others