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Pim-1 kinase-IN-14

SKU: orb3173472

Description

Pim-1 kinase-IN-14 is an inhibitor of PIM-1 kinase, with an IC50 value of 94 nM. It exhibits a broad spectrum and potent anticancer activity against various human cancer cell lines, including liver cancer (HepG-2), colon cancer (Caco-2), myeloid leukemia (NFS-60), and prostate cancer (PC-3) cells. The anticancer effects of Pim-1 kinase-IN-14 are mediated through the induction of apoptosis and the activation of caspase3/7. This compound is useful for studying cancers associated with PIM-1 kinase overexpression.

Research Area

Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

TargetCaspase,Pim,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information