PIK5-12d

SKU: orb2277777

Description

PIK5-12d is a PROTAC-based degrader of PIKfyve that induces pronounced cytoplasmic vacuolization and disrupts autophagy. It demonstrates antitumor activity, inhibiting cancer cell proliferation, and serves as a valuable research tool for studying prostate cancer mechanisms in both cellular and animal models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• MW: 973.19
• Purity: 99.90% (May vary between batches)
• Formula: C₅₂H₆₄N₁₀O₇S
• SMILES: CC1=CC=CC(/C=N/NC2=NC(OCCC3=CC=C(NC(CCCCC(N[C@H](C(N4C[C@H](O)C[C@H]4C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)C(C)(C)C)=O)=O)C=C3)=NC(N7CCOCC7)=C2)=C1
• Target: Autophagy,PROTAC Linker,PROTACs,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510455