Pidnarulex HCl

SKU: orb1739572

Description

Pidnarulex HCl (CX-5461) is a selective RNA polymerase I inhibitor that induces p53-mediated apoptosis in cancer cells via nucleolar stress, without causing DNA damage. It has demonstrated potent in vitro cytotoxicity and robust oral efficacy in vivo across various cancer models, including hematological and solid tumors.

Key Properties

• CAS Number: 2101314-20-7
• MW: 550.08
• Formula: C₂₇H₂₈ClN₇O₂S
• SMILES: Cl.CN1CCCN(CC1)c1ccc2c(n1)n1c3ccccc3sc1c(C(=O)NCc1cnc(C)cn1)c2=O
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131699687