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Picoberin

SKU: orb3174525

Description

Picoberin is a potent inhibitor at low picomolar concentrations, effectively blocking osteoblast differentiation induced by the Hedgehog signaling pathway. As a strong aryl hydrocarbon receptor (AhR) agonist, it also inhibits Wnt3A-induced osteoblast differentiation in C3H10T1/2 cells. Additionally, Picoberin upregulates genes encoding phase I and II metabolic enzymes.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number3034663-23-2
MW362.65
FormulaC17H13BrClNO
SMILESO=C1N2[C@](C=3C(CC2)=CC=CC3)(CC=4C1=CC(Br)=C(Cl)C4)[H]
TargetAryl Hydrocarbon Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information