PI3Kα/HDAC6-IN-1

SKU: orb2277746

Description

PI3Kα/HDAC6-IN-1 is a potent dual inhibitor of PI3Kα (IC50=2.9 nM) and HDAC6 (IC50=26 nM). It suppresses AKT phosphorylation and increases acetylated α-tubulin, demonstrating strong anti-proliferative activity in vitro, such as against multiple myeloma L-363 cells (IC50=0.17 µM), making it a valuable research tool for oncology and signaling pathway studies.

Research Area

Epigenetics & Chromatin

Key Properties

• MW: 669.7
• Formula: C₂₇H₃₀F₃N₇O₆S₂
• Target: PI3K,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PI3K,HDAC