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PI3K/Akt/mTOR-IN-5

SKU: orb2664434

Description

PI3K/Akt/mTOR-IN-5 (D3), a Pseudolaric Acid B derivative, demonstrates antitumor activity by targeting the PI3K/AKT/mTOR and STAT3/GPX4 pathways. This mechanism inhibits proliferation, reduces colony formation, and induces S/G2/M phase arrest and apoptosis in HCT-116 cells, supporting its application in oncology research for in vitro studies.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetPI3K,Akt,mTOR,Apoptosis,STAT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information