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PI3Kα-IN-8

SKU: orb1686565

Description

PI3Kα-IN-8 is a potent and selective PI3Kα inhibitor (IC50: 12 nM). Its mechanism involves inducing oxidative stress, reducing mitochondrial membrane potential, and triggering apoptosis, making it a valuable tool for studying PI3Kα-driven cancers in cellular models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

MW507.42
FormulaC26H27BrN4O2
TargetApoptosis,PI3K,Reactive Oxygen Species,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information