PI3K-IN-56

SKU: orb3028256

Description

PI3K-IN-56 (Compound 1) is an orally active, potent, and selective irreversible inhibitor of phosphoinositide 3-kinase (PI3K). It irreversibly blocks the production of phosphatidylinositol-3,4,5-trisphosphate (PIP3) and the downstream AKT signaling pathway. PI3K-IN-56 holds promise for research in PI3Kα-driven cancers, such as breast and ovarian cancer.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2633645-58-4
• MW: 631.606
• Formula: C₂₈H₃₂F₃N₉O₅
• SMILES: O=C(OC)NC=1N=CC(C=2N=C(C3=CC(=CN3N2)CN4CCN(C(=O)CNC(=O)C=C)CC4)N5CCOCC5)=C(C1)C(F)(F)F
• Target: PI3K,Akt

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PI3K,Akt