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PI3K-IN-47

SKU: orb2278356

Description

PI3K-IN-47 (Compound 27) is a highly potent bivalent PI3K inhibitor with low nanomolar IC50 values against all PI3K isoforms, most notably 0.44 nM for PI3Kα. It demonstrates robust anti-cancer activity in vitro by inhibiting colony formation, migration, and inducing G1 arrest, and has shown efficacy in suppressing tumor growth in HGC-27 xenograft models in vivo.

Research Area

Signal Transduction

Images & Validation

Key Properties

MW1027.07
FormulaC50H46F4N8O8S2
TargetPI3K

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information