PI3Kδ-IN-24

SKU: orb3135775

Description

PI3Kδ-IN-24 is a selective inhibitor of PI3Kδ with an IC50 value of 0.1 nM. It exhibits significant antiproliferative effects on cancer cell lines that overexpress PI3Kδ. PI3Kδ-IN-24 reduces p-AKT levels and induces cell cycle arrest and apoptosis in tumor cells. This compound is applicable for cancer research, particularly in diffuse large B-cell lymphoma (DLBCL).

Research Area

Signal Transduction

Key Properties

• CAS Number: 3051829-20-7
• MW: 527.57
• Formula: C₂₈H₂₉N₇O₄
• SMILES: N([C@H](C(=O)N1CCN(C)CC1)C)C=2C3=C(C=CC(=N3)C=4C=C(C(OC5=CC=CC=C5)=O)C(OC)=NC4)N=CN2
• Target: Akt,Apoptosis,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Akt,Apoptosis,PI3K