PI3Kδ-IN-17

SKU: orb1943297

Description

PI3Kδ-IN-17 (Compound S5) is a highly potent and selective inhibitor of PI3Kδ, demonstrating an IC50 of 2.82 nM against the enzyme. It effectively inhibits the proliferation of SU-DHL-6 lymphoma cells (IC50 = 0.035 µM), supporting its use in hematological cancer research, both in vitro and in preclinical in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2768181-63-9
• MW: 487.48
• Formula: C₂₃H₂₄F₃N₇O₂
• SMILES: N(C=1C2=C(C=CC(=N2)C=3C=C(C(F)(F)F)C(OC)=NC3)N=CN1)[C@@H]4CN(C(=O)[C@@H]5CCCN5)CC4
• Target: PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169450711