PI3Kα-IN-14

SKU: orb1943296

Description

PI3Kα-IN-14 (F8) is a highly potent and selective PI3Kα inhibitor (IC50=0.14 nM) that induces loss of mitochondrial membrane potential, G1 phase cell cycle arrest, and apoptosis in U87-MG cells. It also demonstrates broad antiproliferative activity against cancer cell lines such as PC-3, HCT-116, and U87-MG, supporting its utility in oncology research for in vitro mechanism studies.

Research Area

Cell Biology, Signal Transduction

Key Properties

• Target: Apoptosis,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,PI3K