PI3Kα-IN-12

SKU: orb2278395

Description

PI3Kα-IN-12 is a potent and selective PI3Kα inhibitor with an enzymatic IC50 of 1.2 nM. It demonstrates anti-proliferative activity in HCT-116 and U87-MG cancer cells and has shown efficacy in inducing tumor regression in a U87-MG xenograft mouse model, supporting its use in oncology and signal transduction research.

Research Area

Signal Transduction

Key Properties

• MW: 726.84
• Formula: C₂₈H₃₆F₂N₁₀O₅S₃
• Target: PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PI3K