PI-103 Hydrochloride

• Catalog Number: orb1909002
• Category: Small Molecules
• Description: PI-103 Hydrochloride is a potent dual inhibitor of PI3K and mTOR, demonstrating inhibitory IC50 values of 8 nM for p110α, 88 nM for p110β, 48 nM for p110δ, 150 nM for p110γ, 20 nM for mTORC1, and 83 nM for mTORC2, respectively. Additionally, it inhibits DNA-PK with an IC50 of 2 nM and induces autophagy [1] [2] [3] [4].
• CAS Number: 371935-79-4
• Purity: 98.00%
• MW: 384.82
• SMILES: Cl.Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1
• Formula: C₁₉H₁₇ClN₄O₃
• Biological Activity: PI-103 Hydrochloride is a potent dual inhibitor of PI3K and mTOR, demonstrating inhibitory IC50 values of 8 nM for p110α, 88 nM for p110β, 48 nM for p110δ, 150 nM for p110γ, 20 nM for mTORC1, and 83 nM for mTORC2, respectively. Additionally, it inhibits DNA-PK with an IC50 of 2 nM and induces autophagy [1] [2] [3] [4].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.