Physostigmine Salicylate

SKU: orb1310908

Description

Physostigmine is a reversible cholinesterase inhibitor of natural origin, isolated from the Calabar bean. This parasympathomimetic alkaloid is widely used in research to study cholinergic signaling, with applications in both in vitro enzyme assays and in vivo models of neurodegenerative conditions.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 57-64-7
• MW: 413.48
• Purity: 99.10% (May vary between batches)
• Formula: C₂₂H₂₇N₃O₅
• SMILES: OC(=O)c1ccccc1O.[H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)NC)ccc1N2C
• Target: Cholinesterase (ChE),AChR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.84 mM);DMSO:50 mg/mL (120.92 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cholinesterase (ChE), Alzheimer's, AChE, AChR, barrier, blood-brain, antidote, Inhibitor, Eserine, inhibit, Physostigmine Salicylate, Physostigmine

Compound Identifiers

PubChem CID

657348