Physostigmine

SKU: orb3174449

Description

Physostigmine is an alkaloid extracted from the poison bean (Physostigma venenosum) and acts as a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine inhibits the action of acetylcholinesterase, increasing acetylcholine levels, and thus serves as an antidote for anticholinergic poisoning. Physostigmine crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease.

Key Properties

• CAS Number: 57-47-6
• MW: 275.35
• Formula: C₁₅H₂₁N₃O₂
• SMILES: C[C@]12C=3C(N(C)[C@]1(N(C)CC2)[H])=CC=C(OC(NC)=O)C3
• Target: Cholinesterase (ChE)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Cholinesterase (ChE)