Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Physalin H

SKU: orb1681903

Description

Physalin H is a Hedgehog signaling inhibitor that blocks GLI1-DNA complex formation and exhibits quinone reductase induction. It demonstrates immunosuppressive effects on T cells in vitro and in vivo, along with cytotoxic activity against various cancer cell lines and leishmanicidal activity against Leishmania major promastigotes.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number70241-09-7
MW562.99
FormulaC28H31ClO10
SMILESC[C@]12[C@]34[C@]5([C@@]6(C)[C@@](CO[C@](O3)(C5=O)[C@]7([C@](CC[C@@]4(O)C(=O)O1)([C@]8(C)[C@@](Cl)([C@H](O)C7)CC=CC8=O)[H])[H])(C(=O)O[C@@H]2C6)[H])[H]
TargetAntifection,gp120/CD4,Hedgehog/Smoothened,Endogenous Metabolite,Autophagy

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • physalin F [orb1219606]

    >98% (HPLC)

    57423-71-9

    526.5

    C28H30O10?

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information