Phosphatase-IN-1

SKU: orb1944435

Description

Phosphatase-IN-1 (II-8) is a propranolol-derived inhibitor of phosphatidate phosphatase (Pah1) with a 19.8 μM affinity for MoPah1. It demonstrates antifungal activity against plant pathogens in vitro and shows growth inhibition without toxicity to rice and wheat in vivo studies.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 2889356-55-0
• MW: 344.21
• Purity: 99.88% (May vary between batches)
• Formula: C₁₆H₁₆Cl₂FNO₂
• SMILES: FC1=CC=C(C=C1)CNCC(O)COC2=CC=C(Cl)C=C2Cl
• Target: Phosphatase,Antifungal

Bioactivity

• In Vitro:
  Phosphatase-IN-1 (II-8) exhibits broad-spectrum inhibitory activity against 8 plant pathogens at a concentration of 60 μM and directly binds to MoPah1.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PAH, Fungal

Compound Identifiers

PubChem CID

168510550